Blebbistatin molecular weight
Web(±)-Blebbistatin (±)-Blebbistatin, CAS 674289-55-5, is a cell-permeable, selective, and reversible inhibitor of nonmuscle myosin II. Blocks cell blebbing and disrupts cell migration & cytoKinesis in vertebrate cells.; ... Molecular Weight: 292.33. NACRES: NA.77. … WebMay 30, 2012 · In vitro, blebbistatin inhibits vertebrate striated muscle and nonmuscle myosin II isoforms as well as Dictyostelium discoideum (Dd) myosin II by about 95%, with an IC 50 of 0.5–5 μM ().Vertebrate smooth muscle and Acanthamoeba myosin II are incompletely inhibited even at high blebbistatin concentrations. In vivo experiments …
Blebbistatin molecular weight
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WebBiological Activity (S)-(-)-Blebbistatin is a selective inhibitor of myosin II ATPase activity (IC 50 ~0.5 - 5 μM); active enantiomer of (±)-blebbistatin.Inhibits contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly. (S)-(-)-Blebbistatin rapidly and reversibly blocks cell blebbing, and disrupts directed cell migration and cytokinesis in … WebJan 5, 2024 · Blebbistatin is a potent and selective myosin II inhibitor with IC50s ranging from 0.5 to 5 μM. Blebbistatin potently inhibits several striated muscle myosins as well …
WebSelective inhibitor of myosin II ATPase activity. Inactive enantiomer of (±)-blebbistatin (Cat. No. 1760) Shop (R)-(+)-Blebbistatin, Tocris Bioscience™ at Fishersci.com Fisher Scientific ... Molecular Formula: … WebMay 16, 2013 · Molecular weight. 292.34. Molecular formula. C 18 H 16 N 2 O 2. PubChem identifier. 3476986. Storage instructions. Store at +4°C. Store under desiccating conditions. ... -blebbistatin (ab120425), by ICC/IF. Decreased membrane expression of paxillin correlates with increased concentration of (+/-)-blebbistatin, as described in …
WebMolecular Weight: 292.33: Formula: C 18 H 16 N 2 O 2. CAS No. 856925-71-8: Storage: 3 years -20°C(in the dark) powder 2 years -80°C(in the … WebJun 13, 2005 · blebbistatin (CHEBI:75388) Affected organisms Not Available Chemical Identifiers UNII 8WII7624I5 CAS number Not Available InChI Key LZAXPYOBKSJSEX-GOSISDBHSA-N ... Molecular Weight 227868.56 Da. References. Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data …
WebWhat is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol? Enter 197.13 into the …
WebBlebbistatin is a myosin inhibitor mostly specific for myosin II. [1] [2] It is widely used in research to inhibit heart muscle myosin, non-muscle myosin II , and skeletal muscle … childers tallahasseeWebPreparing Stock Solutions for (±)-Blebbistatin. The following data is based on the product molecular weight 292.34. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions. go to sciencedaily.comWebIn the presence of blebbistatin, the initial rapid fluorescence increase was followed by a quench phase (k obs = 0.03 s –1 at 7.5 μ m blebbistatin and 0.18 s –1 at 50 μ m blebbistatin) leading to a fluorescence level that is 5–10% lower than that of apoS1. Traces were normalized to their starting values. go to school和go to the schoolWebMay 31, 2016 · Blebbistatin is a commonly used molecular tool for the specific inhibition of various myosin II isoforms both in vitro and in vivo. Despite its popularity, the use of blebbistatin is hindered by ... go to school 和 go to the school 的区别WebMolecular Formula: C 18 H 16 N 2 O 2 Molecular Weight: 292.34 Percent Composition: C 73.95%, H 5.52%, N 9.58%, O 10.95% go to school和go school的区别Web(-)-Blebbistatin is a selective cell-permeable inhibitor of non-muscle myosin II ATPases (Kovács et al.; Straight et al.). It rapidly and reversibly inhibits Mg-ATPase activity and in … go to school 和 go to the schoolWebBlebbistatin is a myosin inhibitor mostly specific for myosin II. [1] [2] It is widely used in research to inhibit heart muscle myosin, non-muscle myosin II , and skeletal muscle myosin. Blebbistatin has been especially useful in optical mapping of the heart, [3] and its recent use in cardiac muscle cell cultures has improved cell survival time. go to school with your sims mod