Dl-buthionine-sulfoximine
WebL-Buthionine- (S,R)-sulfoximine is an irreversible inhibitor of γ-glutamylcysteine synthetase (K i = 25 µM). 1 It inhibits the proliferation of ZAZ and M14 melanoma cells, as well as A2780 ovarian and MCF-7 breast cancer cells (IC 50 s = 4.9, 18, 8.5, and 26.5 µM, respectively). 2 L-Buthionine- (S,R)-sulfoximine (100µM) induces ferroptosis ... http://sdos.lib.ntnu.edu.tw/search.result.jsp?query_term1=00456535&query_term2=&query_term3=&index_1=issn_search&class=keywords&datas=dl-buthionine-%28S%2CR%29-sulfoximine
Dl-buthionine-sulfoximine
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WebButhionine sulfoximine (BSO) induces decreased glutathione (GSH) and trypanothione [T(SH) 2] pools in trypanosomatids, presumably because only gamma-glutamylcysteine synthetase (γECS) is blocked.However, some BSO effects cannot be explained by exclusive γECS inhibition; therefore, its effect on the T(SH) 2 metabolism pathway in Trypanosoma … WebProduct name : DL-Buthionine-sulfoximine Product Number : 19176 Brand : Sigma REACH No. : A registration number is not available for this substance as the substance or its uses are exempted from registration, the annual tonnage does not require a registration or the registration is envisaged for a later registration deadline.
WebD,L-Buthionine-(S,R)-sulfoximine is dissolved in sterile 0.9% saline, filtered through a 0.2-p.m polysulfone membrane filter, and administered by 48-h continuous iv. infusion …
WebDL-Buthionine-(S,R)-sulfoximine has been used to deplete cellular glutathione levels in retinal ganglion cell 5 (RGC-5) cell line; DL-buthionine-SR-sulfoximine (BSO) is an amino acid analogue, which acts as an inhibitor of γ-glutamylcysteine synthetase; This … WebIn the presence of DL-buthionine-[S, R]-sulfoximine (BSO), a glutathione synthesis inhibitor, exogenously administered cyst(e)ine did not change the intracellular glutathione content, but increased the intracellular cysteine as well as cystine level. Addition of exogenous cyst(e)ine following 5 mm BSO treatment significantly increased cell ...
WebEugenol is widely used as a food flavoring agent and a dental analgesic. Mice treated with eugenol (400-600 mg/kg, po) in combination with an inhibitor of glutathione (GSH) …
WebActivation of Nrf2 was associated with activation of its downstream targets, such as heme oxygenase-1 (HO-1) and glutamate cysteine ligase catalytic subunit (GCLC). In contrast, DL-buthionine-[S,R]- sulfoximine (BSO), a known GSH-depleting agent, did not increase Nrf2 protein expression or cause its nuclear accumulation. empty homes loanWebL- Buthionine Sulfoximine - CAS 83730-53-4 - Calbiochem. Synonym(s): L- Buthionine Sulfoximine ... 222.31. Compare Product No. Description SDS Pricing; 5.08228: Expand. Hide. Match Criteria: Product Name, Keyword. All Photos (4) DL-Buthionine-(S,R)-sulfoximine. Linear Formula: CH 3 (CH 2) 3 S(O)(=NH)CH 2 CH 2 CH(NH 2)CO 2 H. … draw textures blenderWebDL-Buthionine-sulfoximine is suitable for use to: examine whether the inhibition of glutathione by BSO enhances the apoptotic effect of estrogen on antihormone … empty homes initiative pkcWebDL Science Teacher Streamwood High School ... The pro-oxidant buthionine sulfoximine (BSO) reduces tumor growth of implanted Lewis lung carcinoma in mice associated with increased protein carbonyl ... empty homes in moreno valleyWebDL-Buthionine-Sulfoximine (BSO, DL-Buthionine-(S,R)-sulfoximine) is an inhibitor of glutathione (GSH) synthesis. CAS No. 5072-26-4 Selleck's DL-Buthionine-Sulfoximine … empty homes londonWebFeb 14, 2024 · MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。Insulin R/CD220 Protein, Human (Biotinylated, HEK293, His)品牌：MedChemExpress (MCE)Drug_Names：Insulin R/CD220 Protein, Human (Biotinylated, HEK293, His)Catalog_No empty homes listWebDL-Buthionine-(S,R)-sulfoximine is a potent inhibitor of glutamylcysteine synthetase biosynthesis. - Mechanism of Action & Protocol. From 11:00 pm to 12:00 pm EST ( 8:00 pm to 9:00 pm PST ) on January 6th, the website will be under maintenance. draw text wpf