WebJul 27, 2011 · Its binding to scaffolding polyubiquitin plays a key role in IKK activation by multiple signaling receptor pathways. Can recognize and bind both 'Lys-63'-linked and linear polyubiquitin upon cell stimulation, with a much highr affinity for linear polyubiquitin. Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity. WebMar 21, 2024 · Entrez Gene Summary for NFKBIA Gene. This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the …
Human Gene IKBKG (ENST00000594239.6) from GENCODE V43
http://www.innatedb.com/getGeneCard.do?id=132962 WebMar 21, 2024 · PSMA1 (Proteasome 20S Subunit Alpha 1) is a Protein Coding gene. Diseases associated with PSMA1 include Mucocele Of Salivary Gland and Anthracosilicosis.Among its related pathways are Regulation of activated PAK-2p34 by proteasome mediated degradation and Assembly of the pre-replicative complex.Gene … small picnic table for kids
NFKBIA Gene - GeneCards IKBA Protein IKBA Antibody
WebDescription: Homo sapiens nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (NFKB1), transcript variant 1, mRNA. RefSeq Summary (NM_003998): This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific … WebDescription: This chain was obtained from a monoclonal antibody against 3,4-pyruvylated galactose and isolated from a patient with Waldenstrom's macroglobulinemia. (from UniProt P01763) Gencode Transcript: ENST00000390624.3 Gencode Gene: ENSG00000211964.3 Transcript (Including UTRs) Position: hg38 chr14:106,537,810-106,538,344 Size: 535 … WebActivation of the FCERI engages CARMA1, BCL10 and MALT1 complex to activate NF-kB through PKC-theta (Klemm et al. 2006, Chen et al. 2007). FCERI stimulation leads to … small pics of cameras