Microsomal triglyceride transfer protein是什么意思
WebMicrosomal triglyceride transfer protein (MTP) is observed in the lumen of the endoplasmic reticulum. It is responsible for the transfer of TGs and other lipids from their site of synthesis in the endoplasmic reticulum into the lumen during the assembly of VLDLs [208,209]. VLDLs produced by the liver are the major sources of LDLs in plasma. http://literature.ipathology.cn/article/36412.html#:~:text=%E5%BE%AE%E7%B2%92%E4%BD%93%E7%94%98%E6%B2%B9%E4%B8%89%E9%85%AF%E8%BD%AC%E7%A7%BB%E8%9B%8B%E7%99%BD%20%28microsomal,triglyceride%20transfer%20protein%2CMTP%29%E6%98%AF%E4%B8%80%E7%A7%8D%E4%B8%BB%E8%A6%81%E5%88%86%E5%B8%83%E4%BA%8E%E8%82%9D%E7%BB%86%E8%83%9E%E3%80%81%E8%82%A0%E4%B8%8A%E7%9A%AE%E7%BB%86%E8%83%9E%E4%B8%AD%E7%9A%84%E8%84%82%E8%B4%A8%E8%BD%AC%E7%A7%BB%E8%9B%8B%E7%99%BD%2C%E5%85%B6%E5%9C%A8%E7%94%98%E6%B2%B9%E4%B8%89%E9%85%AF%E8%BD%AC%E8%BF%90%E5%8F%8A%E6%9E%81%E4%BD%8E%E5%AF%86%E5%BA%A6%E8%84%82%E8%9B%8B%E7%99%BD%E7%BB%84%E8%A3%85%E5%92%8C%E5%88%86%E6%B3%8C%E4%B8%AD%E5%8F%91%E6%8C%A5%E7%9D%80%E9%87%8D%E8%A6%81%E4%BD%9C%E7%94%A8.%E8%BF%91%E6%9D%A5%E7%A0%94%E7%A9%B6%E8%A1%A8%E6%98%8EMTP%E4%B8%8E%E8%A1%80%E8%84%82%E9%9A%9C%E7%A2%8D%E5%92%8C%E8%82%9D%E8%84%8F%E8%84%82%E8%82%AA%E5%8F%98%E6%80%A7%E7%AD%89%E7%96%BE%E7%97%85%E7%9A%84%E5%8F%91%E7%94%9F%E5%8F%91%E5%B1%95%E5%85%B3%E7%B3%BB%E5%AF%86%E5%88%87.
Microsomal triglyceride transfer protein是什么意思
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Webミクロソームトリグリセリド輸送タンパク質大サブユニット（ミクロソームトリグリセリドゆそうタンパクしつだいサブユニット、英: microsomal triglyceride transfer protein … WebAbsence of Microsomal Triglyceride Transfer Protein in Individuals with Abetalipoproteinemia John R. Wetterau,* Lawrence P. Aggerbeck, Marie-Elisabeth Bouma, Claude Eisenberg, Anne Munck, Michel Hermier, Jacques Schmitz, Gerard Gay, Daniel J. Rader, Richard E. Gregg Abetalipoproteinemia is a human genetic disease that …
WebThe MTTP gene provides instructions for making a protein called microsomal triglyceride transfer protein. This protein helps produce beta-lipoproteins, which are molecules that … WebMicrosomal triglyceride transfer protein (MTP) is a member of a group of proteins that are able to transfer of lipids between membranes. MTP is an 894 amino acid (97 kDa) …
WebMicrosomal triglyceride transfer protein (MTP) is a member of a group of proteins that are able to transfer of lipids between membranes. MTP is an 894 amino acid (97 kDa) … Web9 okt. 2007 · Microsomal triglyceride transfer protein (MTP) is essential for the assembly of neutral-lipid-rich apolipoprotein B (apoB) lipoproteins. Previously we reported that the Drosophila MTP transfers phospholipids but does not transfer triglycerides. In contrast, human MTP transfers both lipids. To explore the acquisition of triglyceride transfer …
Web1 apr. 2024 · Microsomal triglyceride transfer protein regulates endogenous and exogenous antigen presentation by group 1 CD1 molecules. FoxO1 mediates insulin …
Web3 jan. 2013 · Mechanism of action. Within the lumen of the endoplasmic reticulum, lomitapide inhibits microsomal triglyceride transfer protein (MTP), which prevents the formation of apolipoprotein B, and, thus, the formation of VLDL and chylomicrons as well. Altogether, this leads to a reduction of low-density lipoprotein cholesterol. robert w wright obituaryWebcharacterization of a bovine liver protein capable of transfer- ring triglyceride and cholesteryl ester. This is the first re- ported intracellular protein which has a high specificity for triglyceride and cholesteryl ester transfer. This transfer pro- tein is also unique in that it is associated with the microsomal fraction. robert w woodruff arts centerWebLa MTTP (« microsomal triglyceride transfer protein ») est une protéine dont le gène est du même nom, intervenant dans le métabolisme des lipides. Structure [ modifier modifier le code ] Elle est constituée de deux sous-unités : une … robert w woodruff foundationWeb8 aug. 2008 · Its mechanism involves inhibition of microsomal triglyceride transfer protein, resulting in a reduction of LDL cholesterol. Earlier studies in patients with homozygous FH reveal AEGR-733 is highly effective in lowering LDL cholesterol, yet long term safety and efficacy need to be established. Study Design Go to robert w youngWeb1 apr. 1997 · Microsomal triglyceride transfer protein. Microsomal triglyceride transfer protein Biochim Biophys Acta. 1997 Apr 1;1345(2):136-50. doi: 10.1016/s0005 … robert w yarbroughWeb26 apr. 2007 · Microsomal triglyceride transfer protein (MTP) −493 G/T polymorphism modulates circulating lipid and lipoprotein levels in different subsets and has been linked to NAFLD. The impact of MTP −493 G/T polymorphism, adipokines, and diet on postprandial lipoprotein profile and liver disease was assessed in nonalcoholic steatohepatitis (NASH). robert w young charlotte ncDas mikrosomale Triglycerid-Transferprotein (MTP) ist ein Proteinkomplex aus zwei Proteinen, der im endoplasmatischen Reticulum (ER) aller Säugetiere lokalisiert ist. MTP katalysiert den Transport und Einbau von Triglyceriden, Cholesterinestern, Phospholipiden und Retinylpalmitat (Vitamin A) vom ER-Lumen in diejenigen Plasmalipoproteine, die mit Apolipoprotein B (Apo B) assoziiert sind (VLDL, IDL, LDL, Chylomikronen). Weiters nimmt MTP am Recycling des antigen-präsentierend… robert w woodruff library auc