WitrynaDRC1 is a subunit of the nexin-dynein (see 603335) regulatory complex, an axonemal structure critical for regulation of ciliary dynein motors (Wirschell et al., 2013). Cloning and Expression By searching databases for the human ortholog of Chlamydomonas Drc1, Wirschell et al. (2013)identified DRC1, which they called CCDC164. Witryna1 dzień temu · However, this coherence did not extend to additional elements of the cilia beating machinery. For example, the Nexin Dynein Regulatory Complex (N-DRC) is a key regulator of ODA function, but the N-DRC component CCdc65 (Austin-Tse et al., 2013; Horani et al., 2013) displayed far faster kinetics than did the ODA subunits (Fig. …
Cells Free Full-Text Ciliary Dyneins and Dynein Related ... - MDPI
Witryna24 cze 2024 · There are various factors that may regulate the dynein activity, e.g. the nexin-dynein regulatory complex, radial spokes, and central apparatus. In order to understand the basic mechanism of dynein’s oscillatory movement, we constructed a simple model system composed of MTs, outer-arm dyneins, and crosslinks between … Witryna15 lut 2005 · Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. May play a role in the assembly of N-DRC. May be required for sperm motility. By similarity GO … city of edinburgh council child protection
Ciliary Abnormalities in Antrochoanal Polyps JIR
Witryna21 sty 2024 · The N-DRC is localized between doublet microtubules and has been extensively studied in the unicellular flagellate Chlamydomonas. Recently, it has been … Witryna29 mar 2024 · DRC1 dynein regulatory complex subunit 1 [ (human)] Gene ID: 92749, updated on 3-Apr-2024. Summary. This gene encodes a central component of the … Witryna5 sie 2024 · This gene encodes a central component of the nexin-dynein complex (N-DRC), which regulates the assembly of ciliary dynein. Mutations in this gene can cause ciliary dyskinesia. [provided by RefSeq, Aug 2015] Expression Restricted expression toward testis (RPKM 14.3) See more Orthologs mouse all NEW Try the new Gene … donna wrubel coventry ct